CROI 2014: Hepatitis Coinfection
This year there have been huge medicinal advances in Hepatitis C therapy. The new treatments are a significant improvement over the past. We may have entered an interferon free era. New protease inhibitors are efficacious. The era of differential responses in people co-infected is essentially over. Response rates to cure Hepatitis C is now in months. Interferon free therapy showed that 6 week combination therapy works. Even patients with advanced liver disease were cured. Achieving a 95-100 percent cure rate seems realistic. Patients should keep in mind however that clearing the Hepatitis C virus does not undo liver damage sustained from infection.
Michael Saag, MD, Professor of Medicine, UAB, Birmingham, AL;
Daniel Fierer, MD, Assistant Professor of Medicine, Infectious Diseases, Mount Sinai, Hospital, New York City;
Anita Kohli, MD, Physician Investigator, National Institutes of Health, Bethesda, MD, and Leidos Biomedical Inc. Bethesda, MD;
Arthur Kim, MD, Assistant Professor of Medicine, Massachusetts General Hospital, Boston, MA;
Host – Liz Highleyman, Editor in Chief, HIV and Hepatitis.com, San Francisco, CA